Common non-anthracycline antitumor antibiotics include which of the following?

Bleomycin is classified as a non-anthracycline antitumor antibiotic. It is primarily used in the treatment of certain types of cancer, including testicular cancer and lymphomas. Bleomycin works by causing breaks in DNA strands, which ultimately leads to cell death, making it effective at targeting rapidly dividing cancer cells.

Doxorubicin, while also an antitumor antibiotic, is an anthracycline, which places it in a different subclass. Cytarabine is a nucleoside analog that acts as a chemotherapy agent but does not fall into the antibiotic category. Similarly, 5-FU (5-fluorouracil) is a chemotherapy drug that acts as an antimetabolite and is not classified as an antitumor antibiotic. Thus, the correct identification of Bleomycin as a non-anthracycline antitumor antibiotic underscores the difference in drug classifications within cancer treatment.