Which of the following is a common side effect of aromatase inhibitors?

Aromatase inhibitors, commonly used in the treatment of hormone receptor-positive breast cancer, are associated with various side effects due to their mechanism of action, which significantly reduces estrogen levels in the body. A common side effect of aromatase inhibitors is nausea and vomiting, which results from the disruption of normal hormonal balance and can affect gastrointestinal function.

Patients may also experience changes in appetite and digestive issues as a consequence of lowered estrogen levels, ultimately leading to nausea. While other side effects like headaches and memory loss can occur, nausea and vomiting are typically more pronounced and distressing for patients. Enhanced libido is generally not a side effect of aromatase inhibitors, given that they reduce estrogen, which in turn can negatively impact sexual desire in some individuals. Understanding these side effects is crucial for managing them effectively during treatment.